Lipogems® Canine is a new innovative application of regenerative technology available from referral veterinary surgeons for a range of conditions including orthopaedic and soft tissue injuries and diseases including osteoarthritis. Veterinary treatment for you dog can be considered by asking your first referral veterinary surgeon to refer your case to one of our centres. To find a referral centre click here. #lipogemscanine
Saving Your Best Friend
What is Lipogems®?
What is a Pericyte?
Pericytes are contractile cells that wrap around the endothelial cells of capillaries and venules throughout the body.
Pericytes to MSC's and what they do:
Lipogems® preserves viable elements with Pericyte identity that, after an injury, detach from the capillaries and gradually convert into activated Mesenchymal Stromal Cells (MSC's).
What are MSC's?
Mesenchymal Stromal Cells, or MSCs, are multipotent stromal cells that can differentiate into a variety of cell types, including: osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells).
Lipogems® Canine is a new innovative application of regenerative medicine, it is unlike any other regenerative therapy available for treating your dog. Unlike many other veterinary treatments Lipogems® has come from the human medical world to the veterinary world with a background of extraordinary results. To see how the treatments have worked for dogs of all breeds and backgrounds click here. If you are a vet and would like to read our comprehensive presentation on the science behind Lipogems® Canine complete with case studies and links for further reading click here.
Lipogems® works by micro-fragmenting adipose tissue (tissue harvested from fat) obtained from Lipoaspirates, through a non-enzymatic, mechanical processing using the closed system and disposable device. Adipose tissue is harvested using a vacuum syringe from around the flank of the dog.The harvested fat tissue using the Lipogems® device is washed in saline and gently agitated so that the all-important Pericytes detach from small vessels and activate. These cells with the stromal vascular structure of adipose tissue acts as a local scaffold to maintain regenerative activity for many months.The whole procedure from harvesting to the injection is completed in less than 40 minutes under general anaesthetic. One of the important points about this procedure is that it is quick to perform and promotes healing as early as 10 days after treatment and involves very little requirement for drug usage. To find out what kind of injuries can be treated click here.
How did Lipogems® begin?
Pioneered by Dr. Carlo Tremolada, a renowned Italian maxillofacial plastic surgeon, who was searching for a way to create a smoother, more viscous fat graft for filling defects and creating natural volumetric enhancement of the face.
Unexpectedly, his patients experienced a significant decrease in bruising and inflammation normally associated with these procedures, and demonstrated substantial regenerative effects on the underlying tissues.
Subsequently, scientific colleagues at the University of Miami, the Pasteur Institute in Paris, and UCLA, have identified and validated unique regenerative characteristics within the Lipogems®.
The Lipogems® system received FDA 510(k) clearance in the U.S in December of 2014.
The efficient closed-loop device, initially used only in plastic and reconstructive surgery, showed remarkable benefits for orthopaedic indications, opening enormous market potential. Dogs within the UK can now be treated by veterinary surgeons trained by the Lipogems® Canine and Lipocast Biotech UK team. To read more about the science of Lipogems® click here, and to find out more about human application click here.